HCC-1, CCL14 (66 a.a.), human

Thương hiệu: Bio Basic-Canada   |   Tình trạng: Còn hàng
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HCC-1, CCL14 (66 a.a.), human
CAT: RC315-25A
DG: No
Storage: (-15 to -20)C

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HCC-1, CCL14 (66 a.a.), human
CAT: RC315-25A
DG: No
Storage: (-15 to -20)C
Sterile: Yes
Stock: Inquire

Product Description: HCC-1, CCL14 (66 a.a.), human: Human CCL14 is belonging to the CC chemokine family. It is encoded by the gene CCL14. CCL14 has two isoforms, CCL14a (HCC-1) and CCL14b (HCC-3). The sequence of HCC-3 differs from HCC-1 as follow: 27-27 R→ QTGGKPKVVKIQLKLVG. CCL14 was first isolated from the hemofiltrate of human patients with chronic renal failure. The N-terminal processed forms HCC-1(3-74), HCC-1(4-74) and HCC-1(9-74) are produced in small amounts by proteolytic cleavage after secretion in blood. CCL14 promotes chemotaxis of T lymphocytes, monocytes and eosinophils, and inhibits infection of M-tropic human immunodeficiency virus type 1 and is a ligand for CCR1, CCR3 and CCR5. Recombinant human CCL14 (66 a.a.) contains 66 amino acid residues and activation of the HCC 1/CCL14a precursor to active peptide is mediated by the urokinase type plasminogen activator or plasmin., UnitProt ID: Q16627

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