I-TAC, CXCL11, human

Thương hiệu: Bio Basic-Canada   |   Tình trạng: Còn hàng
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I-TAC, CXCL11, human
CAT: RC312-22
Purity: >97% by SDS-PAGE and HPLC analyses
Storage: (-15 to -20)C

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I-TAC, CXCL11, human
CAT: RC312-22
Purity: >97% by SDS-PAGE and HPLC analyses
Storage: (-15 to -20)C
Sterile: Yes
Formulation: Lyophilized from a 0.2mm filtered concentrated solution in 20mM PB, pH 7.4, 100mM NaCl

Product Description: I-TAC, CXCL11, human: CXCL11 cDNA encodes a 94 amino acid (aa) residue precursor protein with a 21 aa residue putative signal sequence, which is cleaved to form the mature 73 aa residue protein. CXCL11 shares 36% and 37% amino acid sequence homology with IP-10 and MIG (two other known human non-ELR CXC chemokines), respectively. CXCL11 is expressed at low levels in normal tissues including thymus, spleen and pancreas. The expression of CXCL11 mRNA is radically up regulated in IFN-γ and IL-1 stimulated astrocytes. Moderate increase in expression is also observed in stimulated monocytes. CXCL11 has potent chemoattractant activity for IL-2 activated T cells and transfected cell lines expressing CXCR3, but not freshly isolated T-cells, neutrophils or monocytes., UnitProt ID: O14625

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