IL-33, Interleukin-33, human

Thương hiệu: Bio Basic-Canada   |   Tình trạng: Còn hàng
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IL-33, Interleukin-33, human
CAT: RC212-44
Purity: >97% by SDS-PAGE and HPLC analyses.
Storage: (-15 to -20)C

 

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IL-33, Interleukin-33, human
CAT: RC212-44
Purity: >97% by SDS-PAGE and HPLC analyses.
Storage: (-15 to -20)C
Sterile: Yes
Formulation: Lyophilized from a 0.2μm filtered concentrated solution in 20mM PB, 150mM NaCl, 1mM EDTA, 2mM β-Mercaptoethanol, pH7.4

Product Description: IL-33, Interleukin-33, human: IL33, also known as NFHEV and DVS 27, is a 30 kDa proinflammatory protein that may also regulate gene transcription. IL33 is constitutively expressed in smooth muscle and airway epithelia. It is upregulated in arterial smooth muscle, dermal fibroblasts, and keratinocytes following IL1α or IL1β stimulation. IL-33 shares structural and functional characteristics with the IL-1 cytokine family. It binds and signals through the IL-1RL1/ST2 receptor activating NF-kappaB and MAP kinases. IL-33 induces production of TH2 cell related cytokines, including IL-4, IL-5 and IL-13, and exerts multiple inflammation related bioactivities., UnitProt ID: O95760

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