IL-36 alpha (153 a.a.), murine (mouse)

Thương hiệu: Bio Basic-Canada   |   Tình trạng: Còn hàng
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IL-36 alpha (153 a.a.), murine (mouse)
CAT: RC232-47B
DG: No
Storage: (-15 to -20)C

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IL-36 alpha (153 a.a.), murine (mouse)
CAT: RC232-47B
DG: No
Storage: (-15 to -20)C
Sterile: Yes
Stock: Inquire

Product Description: IL-36 alpha (153 a.a.), murine (mouse): Interleukin-36 (IL-36) is a pro-inflammatory cytokine which plays an important role in the pathophysiology of several diseases. IL-36α, IL-36β, and IL-36γ (formerly IL-1F6, IL-1F8, and IL-1F9) are IL-1 family members that signal through the IL-1 receptor family members IL-1Rrp2 (IL-1RL2) and IL-1RAcP. IL-36α is mainly found in skin and lymphoid tissues, but also in fetal brain, trachea, stomach and intestine. It is expressed by monocytes, B and T cells. Notably, IL-36 alpha is the only novel IL-1 family member expressed on T-cells. Recombinant murine interleukin-36 alpha contains 153 amino acids residues which is a single non-glycosylated polypeptide. Specifically, mouse IL-36α shares 83 % a.a. sequence identity with rat IL-36α, 54 – 60 % with human, rabbit, equine and bovine IL-36α., UnitProt ID: Q9JLA2

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