MIF, rat

Thương hiệu: Bio Basic-Canada   |   Tình trạng: Còn hàng
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MIF, rat
CAT: RC752-14
DG: No
Storage: (-15 to -20)C

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MIF, rat
CAT: RC752-14
DG: No
Storage: (-15 to -20)C
Sterile: Yes
Stock: Inquire

Product Description: MIF, rat: Macrophage migration inhibitory factor (MIF or MMIF), also named as glycosylation-inhibiting factor (GIF), L-dopachrome isomerase, or phenylpyruvate tautomerase, is a protein encoded by the MIF gene. It is released from white blood cells by bacterial antigen stimulation to trigger an acute immune response, or by glucocorticoids to counter-act the inhibitory effects of glucocorticoids on immune system. MIF is a homotrimer of which each subunit contains 115 amino acids. As mentioned above, MIF is involved in the innate immune response to bacterial pathogens and counter-acts the anti-inflammatory activity of glucocorticoids. Furthermore, it also plays a role as mediator in regulating the function of macrophages in host defense and has phenylpyruvate tautomerase and dopachrome tautomerase activity in vitro. Rat MIF is 99 %, 90 %, 89 %, and 89 % a.a. identical to human, murine, porcine and bovine, respectively., UnitProt ID: P30904

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