TNF alpha, Tumor Necrosis Factor-alpha, monkey (rhesus macaque)

Thương hiệu: Bio Basic-Canada   |   Tình trạng: Còn hàng
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TNF alpha, Tumor Necrosis Factor-alpha, monkey (rhesus macaque)
CAT: RC224-12
Purity: > 95 % by SDS-PAGE and HPLC analyses.
Storage: (-15 to -20)C

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TNF alpha, Tumor Necrosis Factor-alpha, monkey (rhesus macaque)
CAT: RC224-12
Purity: > 95 % by SDS-PAGE and HPLC analyses.
Storage: (-15 to -20)C
Sterile: Yes
Formulation: Lyophilized from a 0.2 µm filtered concentrated solution in PBS, pH 7.4, 5 % trehalose.

Product Description: TNF alpha, Tumor Necrosis Factor-alpha, monkey (rhesus macaque): Tumor necrosis factor alpha (TNF-α), also called cachectin, is the best-know member of the TNF-family, which can cause cell death. This protein is produced by neutrophils, activated lymphocytes, macrophages, NK cells, LAK cells, astrocytes endothelial cells, smooth muscle cells and some transformed cells. TNF-α occurs as a secreted, soluble form and as a membrane-anchored form, both of which are biologically active. The naturally-occurring form of TNF-α is glycosylated, but non-glycosylated recombinant TNF-α has comparable biological activity. The biologically active native form of TNF-α is reportedly a trimer. Rhesus macaque and human TNF-α show approximately 98 % homology at the amino acid level. Two types of receptors for TNF-α have been described and virtually all cell types studied show the presence of one or both of these receptor types., UnitProt ID: P48094

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